Digilog Journal

Think tank

Digilog Journal

Idea workshop
(think tank)

As a think tank, we are active in various “collaborative research areas”: currently, we are analyzing and securing access to healthcare in regions with precarious healthcare needs. In this context, ccc develops new research projects in collaboration with other companies, scientific institutions, and clinical institutions, and, in individual cases, participates in funding applications, acting as consortium leader upon request, and in project management.

Digilog Journal

Signature Projects

Digilog Journal

digilog

At the end of the 2010s, we had many discussions late at night and in real, unusual, and virtual locations, which not only gave rise to a small, fine workshop of ideas over the months and years, but also led to the conception of several Signature Projects 2017-2020.

Read More

How it all began: “digilog” (Digital and analog companions for an aging population) was launched as a project within the newly formed “Health Campus” of the Potsdam MWFK.

In 2014, the Brandenburg Medical School (MHB), a private university, was founded, based on ideas from Witten/Herdecke and the now-discontinued reformed medical degree program at the Charité. The expectation that this new institution could sustain itself through tuition fees and develop a competitive research agenda was, as soon became apparent, naive. However, the founding idea of relying on students who qualify for medical studies not through the numerus clausus, but through their documented social and humanitarian commitment, was and remains as correct as it is unique.

The “Health Campus,” which connected the MHB with the University of Potsdam and the Brandenburg University of Technology Cottbus-Senftenberg (b-tu) as supporting universities, was intended to reorganize the health sciences landscape of the state of Brandenburg. Three projects were funded for this purpose, and “digilog” was one of them and ultimately became the most visible. “digilog” brought together ideas that were then being formulated and discussed everywhere on podiums and in podcasts for the first time in a major effort and is the first signature project that stands for innovative forms of care at the intersection of digital breakthroughs and “analog” commitment. In 2019, the first digilog congress was held at the Brandenburg State Representation in Berlin. “digilog” became a brand.

»digilog« built an eHealth Center designed to process a wide variety of information from »digital companions«, such as wearable sensors (wearables and implants), point-of-care tests (POCT), and mobile imaging. This included, for example, an adhesive, 1-7 day sensor platform for a 3-lead ECG, a blood pressure ear sensor, and Apple Watch data, as well as a lab-on-a-chip for mobile diagnostics of biochemical and microbiological parameters, as well as the integration of handheld ultrasound systems at key points of outpatient care.

The first eHealth Center was established as part of digilog on the campus of the RK and MHB in the Fontanestadt Neuruppin and was dedicated to providing care in the RK catchment area between Oranienburg and Wittstock. As part of the new activities in and for Lusatia, a large new eHealth Hub is being established there, again in connection with a funded joint project (R&C.net), which will assume coordinating and support functions for additional regional eHealth Centers in the state of Brandenburg and beyond.
This “hub” is linked to eHealth Centers in other regions to provide them with valid medical support and a data-secure infrastructure upon request. Currently, data streams from cooperating medical practices and hospitals in the Ruppiner Land region are being processed, and other districts will soon be added.

digilog: Conference proceedings

We are pleased to present a collection of articles from the digilog project. These articles present and discuss research projects and products aimed at bridging the gap between analog and digital medicine.

Digilog Journal

Current projects

R&C.net

In 2019, we – the Carl-Thiem-Klinikum gGmbH – were invited to join the Medical Informatics Initiative (MI-I). The MI-I brings together German university hospitals and, in four consortia with different thematic focuses, aims to establish data integration centers at each location, whose data pool will be made available to research groups throughout Germany. We chose the HiGHmed consortium and ccc. Center for Connected Health UG submitted a corresponding application for the CTK, initially as a networking partner, which was accepted by the BMBF, and the “R&C.net” (for research & care: networked) project launched on February 1, 2020.

The cooperation partners are the b-tu and the MHB as two of the three supporting universities of the joint Faculty of Health Sciences (FGW).

  • The CTK’s contribution to HiGHmed lies in the fact that it opens up a unique region for the consortium that is interesting in terms of healthcare and research policy.
  • At the same time, Lusatia is a prototype for increasingly precarious living conditions: sparse settlement, aging population and shrinking supply of services.
  • A significant portion of the investments agreed to mitigate structural change will go into R&D.
  • Although the CTK itself is the largest medical care facility in the state of Brandenburg and currently an academic teaching hospital of the Charité, it is not yet a “research hospital” in the true sense of the word. However, to support this structural change, it is to be expanded into a “Research Hospital 4.0” as part of the “Lusatia Health Model Region” and become a “digital lead hospital.”
  • Almost at the same time, it will become a university hospital and will have to ensure teaching and research for the new, first state-supported medical faculty in the state.

These specifications and framework conditions undoubtedly make medical informatics a constitutive part of the CTK’s identity and its mission. The medical informatics initiative creates important prerequisites for closer ties between research and healthcare. The CTK offers the HiGHmed consortium extensive experience in acquiring mobile data from the outpatient sector, coupled with a rural, non-urban catchment area. Unlike other HiGHmed catchment areas, there are no major cities within it. At the same time, the region is undergoing structural change, which – under changing circumstances – will also affect other regions in Germany, each with its own unique conditions for health and illness.

In the cardiology use case, new mobile diagnostic technologies for the long-term monitoring of chronically ill patients are being tested alongside clinical data. They enable the collection of comprehensive and sometimes highly specific data. This data can be used to detect early signs of deterioration in patients at high risk for cardiovascular disease, thus reducing hospital stays and mortality rates in the long term.

TEAM:EXCHANGE

Cottbus and Lusatia are currently at the center of a structural change that will transform a landscape shaped by mining for more than 100 years into a region that will be dominated by the healthcare industry.

The medical technology sector is diverse. Clinical trials based on the collaboration model between the pharmaceutical industry and hospitals have so far only been conducted for high-risk products. Collaboration is usually direct (without going through a CRO) and primarily with university hospitals. Only since the announcement of the new EU Medical Device Regulation (MDR) have the majority of medical device manufacturers had to address the issue of clinical benefit/risk assessment of their products in a significant way. To date, there have been only a few bridgeheads in healthcare for this, again mostly in university-related settings. This shortage is particularly problematic for medical devices used in outpatient care. The key problems facing many, especially smaller, healthcare companies are access to clinical users and the major hurdles in transferring innovative products into standard care.

This also applies to the majority of products in the digital health sector.

There is a significant demand for clinical services in both sectors. The CTK intends to specifically address this need in the future.

The demand for complete and process solutions as well as for individualized and digitalized applications requires cross-sectoral perspectives: with regard to medical technology and DiGAs no less than with regard to the outpatient and inpatient sectors in everyday care.

The Industry-in-Clinic platform at the CTK (TEAM: exchange) will provide medical technology companies (as well as companies in the digital healthcare industry) with an infrastructure and equipment for the various industry partners, opening up access to medical expertise, clinical trial scenarios and data.

The offer is to provide individual support throughout the product cycle, from the development of an idea to market readiness, while being able to draw on the patients of the state’s largest hospital and the medical-clinical expertise of this facility, as well as the skills and network of the neighboring Technical University. Commercialization should be prepared to facilitate market access and ensure sustainable market penetration.

This platform offers modular, professionalized offerings across the entire value chain.

At the end of the conceptual phase and thus at the start of the testing phase, TEAM: exchange UG is established as an umbrella organization for applied research and transfer services: problem-oriented, diverse expertise and top-class test fields for medical devices (and DiGAs) in preparation for market entry, certification, and recertification. This economically independent umbrella organization collaborates with various clinical partners, including the CTK (Central Clinical Research Center for Medical Devices), the Sana clinics in Cottbus, Senftenberg, Lauchhammer, and beyond, the Diakonissen hospitals in the state of Brandenburg, the Ruppiner clinics, and others, and organizes clinical-technical dialogue formats and “classic” clinical-scientific research projects (clinical studies, RCTs) with the local study centers.

com(m) 2020

The WIR! Alliance
The com(m) 2020 alliance aims to contribute to securing healthcare in Lusatia. com(m) 2020: the acronym stands for the area of need  Community Care” (health in the local community) and focuses on the corresponding innovation field of community care technologies.
This refers to coordinated structural, process, service, and product innovations that create an efficient and effective continuum of care in rural areas, thus defining and communicating healthcare as a factor that creates quality of life and security.

The goals
The challenge is to bridge the spatial and technical distance between healthcare providers and citizens; the com(m) 2020 alliance is based on three cornerstones:  Digital Care is a first cornerstone of community care technologies, which organize low-threshold access to healthcare, and of com(m) 2020. Innovations in the service sector address this need by increasingly offering outpatient services, delegating them to local staff to a reasonable extent, and enabling citizens to help shape their healthcare. Skilled worker development and mobile care are key words for this second cornerstone of com(m) 2020. Future
trends in mobility offer opportunities to remobilize people with disabilities (the disability can be a walking disability or a small, isolated place of residence) and to keep them mobile. Care Logistics is the third cornerstone of com(m) 2020 .

The Alliance Region:
Rural regions share structural problems in many places and are often focal points of demographic and structural change. Southeastern Brandenburg not only shares many problems with Prignitz and Ruppiner Land, but is also facing massive structural change due to the end of mining by 2038 – the most important regional industry for 100 years. The alliance region of com(m) 2020 is Lusatia: across federal states, in several model regions.

THIEM:COTTBUS5G

THIEM:COTTBUS5G answers the question of how 5G could improve healthcare. To do so, we examine the “patient journey” into and through a hospital: how do tailored data transmission technologies change this journey, improve patient safety, and transform the patient experience?

5G and its advantages will be demonstrated using the example of the path taken by a patient with an acute heart attack. The technology will then be expanded to other medical conditions and rolled out beyond the campus, into the city and the region.
Treatment pathways will be digitally coordinated in the background and accelerated through the intelligent distribution of process-relevant information . The material and personnel resources required in individual cases will be recorded and consolidated spatially and temporally, thus taking decisive steps toward evidence-based care and improved quality .

Everything becomes a data source: every ultrasound machine, the CT scanner, the laboratory and intensive care unit capacity, the operating room, and every suitable hospital bed.
Thus, a large hospital tends to have an infinite number of “addresses” of a complex Internet of Things (IoT). However, this is not enough: the necessary human resources must be managed (and instructed): medical, support, and nursing staff, to ensure they are in the right place at the right time.

Along the patient journey, the IoT, initially defined only in technical and informational terms, is being further developed into an Internet of Services (IoS) serving the patient.
Data is being provided to the various hospital areas via the most suitable networks and media: 5G is the “data superhighway.”

The patient journey, based on diverse and absolutely up-to-date information, is paved in the background even before admission: The patient arrives and the hospital’s resources are already awaiting them; the path forward is paved.

Smart Hospital  thus means saving time, providing functions, and leveraging resources more effectively—in short, providing better patient care. The  backbone  of this information revolution in hospitals is 5G. Success will depend on 5G being compatible with other old and new data transmission technologies and,  last but not least,  gaining acceptance for 5G in civil society.

Pipeline (acronyms)
  • anorExyVR
  • Digi-H
  • Digital Twins
  • dSELF
  • EDGE
  • eSTORCH
  • H70 | 160
  • Invisible 5G